Séminaire CulturChem | Morgan Donnard "Captodative aminoalkenes: Great precursors to access original heterocycles"
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Le 20 oct. 2023
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Séminaire
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Sorbonne-Université, campus Pierre et Marie Curie
UFR de Chimie, tour 32-42, 1er étage, salle 101
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Ollivier Cyril
Séminaire CulturChem | Personnalité invitée |
Titre |
CAPTODATIVE AMINOALKENES: GREAT PRECURSORS TO ACCESS ORIGINAL HETEROCYCLES - AMINOALCÈNES CAPTODATIFS : DE GRANDS PRÉCURSEURS POUR ACCÉDER AUX HÉTÉROCYCLES ORIGINAUX
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Présenté par | |
Affectation |
Université de Strasbourg, UMR 7042 LIMA |
Résumé | Captodative enamides are particularly functionalized building blocks, opening up a wide range of applications in synthetic chemistry, particularly in heterocyclic synthesis. However, access to these compounds remains particularly limited, especially in the case of tetrasubstituted C=C double bonds, due to regio- and stereoselectivity problems. In this lecture, we present the selective and efficient synthetic routes to captodative enamides that we have developed. These syntheses are base on ynamide difunctionalizations, and we will then present our first applications of these building blocks to obtain totally original heterocycles, including unprecedented silacyclic fluorophores. |
Contact CulturChem |
Cyril Ollivier |