• Recherche

Séminaire CulturChem | Morgan Donnard "Captodative aminoalkenes: Great precursors to access original heterocycles"

  • Le 20 oct. 2023

  • Séminaire
  • Sorbonne-Université, campus Pierre et Marie Curie
    UFR de Chimie, tour 32-42, 1er étage, salle 101

Séminaire CulturChem Personnalité invitée
Titre
CAPTODATIVE AMINOALKENES: GREAT PRECURSORS TO ACCESS ORIGINAL HETEROCYCLES - AMINOALCÈNES CAPTODATIFS : DE GRANDS PRÉCURSEURS POUR ACCÉDER AUX HÉTÉROCYCLES ORIGINAUX
Présenté par

Morgan Donnard

Affectation

Université de Strasbourg, UMR 7042 LIMA

Résumé Captodative enamides are particularly functionalized building blocks, opening up a wide range of applications in synthetic chemistry, particularly in heterocyclic synthesis. However, access to these compounds remains particularly limited, especially in the case of tetrasubstituted C=C double bonds, due to regio- and stereoselectivity problems. In this lecture, we present the selective and efficient synthetic routes to captodative enamides that we have developed. These syntheses are base on ynamide difunctionalizations, and we will then present our first applications of these building blocks to obtain totally original heterocycles, including unprecedented silacyclic fluorophores.
Contact
CulturChem
Cyril Ollivier