Séminaire PTF RMN | Patrick Berthault "Hyperpolarized species, chemistry and fast methods for high-sensitivity NMR"

Dans le cadre des séminaires de la Plateforme RMN
 

Patrick Berthault
NIMBE, CEA, CNRS, Université de Paris Saclay, CEA Saclay, 91191 Gif-sur-Yvette, France

Présentera un séminaire intitulé
"Hyperpolarized species, chemistry and fast methods for high-sensitivity NMR"

Two research axes of our laboratory focus on the production and use of hyperpolarized species for NMR spectroscopy and imaging.

First, small amounts of aromatic amine-containing molecules in solution are detected very sensitively with parahydrogen in SABRE-type methods. Recent methods extend this approach to a wider range of molecules. But our major activity lies in the use of laser-polarized xenon, either as a diffusive tracer or encapsulated in host systems, for the detection of analytes or biological events. Some examples of applications will be given. The optimized use of these non-equilibrium species, which requires specific protocols and pulse sequences, will also be described.

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