Parcours NMP
Psychiatric disorders are among the main causes of morbidity and mortality worldwide, posing a substantial burden on individuals and society. These disorders are complex multifactorial illnesses involving chronic alterations in neural circuit structure and function. Examples of neuropsychiatric disorders include depression, anxiety, addiction, autism, bipolar disorder, and schizophrenia. These major psychiatric syndromes result from the interaction of several factors including genetic, neurobiological, cultural, and life experiences. Common points of these pathologies rely on dysregulations in cerebral cortex and limbic brain regions implicated in regulating stress responses, reward, and cognition. In particular, dysregulations of synaptic circuits and transcriptional alterations along with alterations in neurotransmission are closely associated with the pathogenesis of psychiatric diseases.
Key words: neuroscience, psychiatric diesases, circuits, signaling pathways, behaviour, neurotransmission
MASTER NMP
Objectives
The aim of the "Neuroscience of Neuropsychiatric Diseases" program is to provide cutting-edge training in the biological mechanisms underlying the pathogenesis of neuropsychiatric diseases. Students will develop both the scientific skills to tackle fundamental questions in neuroscience and the technical skills to be able to respond to society's needs in neuroscience.
The M2S3 is organized as followed:
- Developing your Masters' research project (6ECTS) throughout semester
- Main track-specific courses (18ECTS). Several possibilities apply, as presented below:
- One course upon application (see below) + one or 2 courses from either block 1,2 or 3
- One course from each block (1, 2 and 3)
- Specialized short courses (6ECTS)
- 2 courses to choose from, each in one of the 2 series of Specialized Short Courses (MU5BIN16/MU5BIN17
Main thematic coursework
Courses upon application:
- MU5BIN10 - ENS/SU course in neurophysiology (English; 12 ECTS)
- MU5BIN09 - Pasteur course Development and Plasticity of the Nervous System (English; 12 ECTS)
- MU5BIN15 - ICM course: Brain to Market summer school (English; 6 ECTS)
Applications for these courses must be submitted via e-candidat and will only be considered if accompanied by a letter of motivation.
Mandatory courses (12 ECTS):
- MU5BIN22 Hot topics: transdisciplinary approaches to neurodegenerative and psychiatric diseases (throughout the semester) (6 ECTS)
- MU5BIN25 Understanding psychiatric disorders: from signalling molecules to circuit & behaviour (6 ECTS) - Block 3
Optional mandatory courses (6 ECTS):
- MU5BIN18 Novel technologies applied to human neuropathologies - Block 1
- MU5BIN06 Neurotransmission and Signaling in Health and Disease - Block 2
Recommended Specialized Short Courses (3ECTS) :
- MU5BIN17 Neuropsychiatry Genetics
- MU5BIN17 Pharmacological Approaches in Neuroscience
Lab internship, Master’s thesis
The aim of the research internship is to immerse yourself in a professional research environment where you can apply your academic knowledge to real-world scientific inquiries. This experience will allow you to develop critical research skills, including experimental design, data production and analysis, and scientific communication. Additionally, the internship fosters autonomy, problem-solving, and teamwork, while preparing you for advanced careers in research, industry, or academia. It also provides an opportunity for you to explore potential areas of specialization and to contribute to the broader scientific community through your work.
As part of the M2 program, students are required to complete a lab internship, ideally secured before the start of the third semester (S3). Some labs have already proposed internships, and these opportunities, already validated by the master’s program, will be made available to all students upon enrollment in the M2 track. However, you can also propose your own lab and research topic, which will be submitted to the program directors for approval.
The internship has a maximum duration of six months (5 month minimal period) and can take place either in France or abroad. Depending on the courses followed during your M2S3, you might have a couple of weeks or a month to spend in your hosting lab. This is a unique opportunity to immerse yourself in your internship topic and prepare your presentation for “Developing your Masters research project” evaluation.
The final defense of the internship project will take place either in June, for students applying to a Doctoral School, or in early September for all other students.
Contact
Track Director
Sandrine Betuing
Adminstration Office
Véronique de Surirey
Campus Pierre et Marie Curie
Bâtiment C - 1ere Etage - Porte 105
+33 (0)1 44 27 23 81
9, quai Saint Bernard
Case courrier 118
75252 Paris Cedex 05