• Biologie
  • Santé

Biologie Cellulaire et Cancer

  • Unité mixte de recherche

Publié le 27/04/2020 - Mis à jour le 13/12/2024

Équipes

Direction

  • Franck Perez

Direction adjointe

  • Renata Basto

Publications sur HAL - Archive ouverte

Toutes les publications sur HAL
  • Article dans une revue

VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement

Somya Vats, Pedro Dionisio, Quentin Lemercier, Raphael Pineau, Ludivine Therreau, Joanna Lipecka, Béatrice Cholley, Jean-Baptiste Moog, Jose Wojnacki, Céline Keime, Diana Zala, Philippe Bun, Sofia Freire, Neuza Domingues, Lydia Danglot, Ida Chiara Guerrera, Cédric Delevoye, Eric Chevet, Nuno Raimundo, Thierry Galli

Late endosomal secretion is an unconventional secretion mechanism that depends on the SNARE protein VAMP7. We previously showed that VAMP7 mediates the secretion of the ER protein Reticulon3. However, the functional relevance and molecular mechanism of this secretory pathway remain unclear. Here,…

Nature Communications, 2026, ⟨10.1038/s41467-026-69900-4⟩. ⟨inserm-05532465⟩

  • Article dans une revue

sCellST predicts single-cell gene expression from H& E images

Loïc Chadoutaud, Marvin Lerousseau, Daniel Herrero-Saboya, Julian Ostermaier, Jacqueline Fontugne, Emmanuel Barillot, Thomas Walter

Understanding the spatial organization of individual cell types within tissue and how this organization is disrupted in disease, is a central question in biology and medicine. Hematoxylin and eosin-stained slides are widely available and provide detailed morphological context, while spatial gene…

Nature Communications, 2026, 17 (1), pp.1194-1194. ⟨10.1038/s41467-025-67965-1⟩. ⟨hal-05502878⟩

  • Article dans une revue

Regulation of cell dynamics by rapid integrin transport through the biosynthetic pathway

Martina Lerche, Mathilde Mathieu, Hellyeh Hamidi, Megan Chastney, Guillaume Jacquemet, Bart Marlon Herwig Bruininks, Shreyas Kaptan, Lene Malerød, Nina Marie Pedersen, Andreas Brech, Nobuyuki Matoba, Yuichiro Sato, Ilpo Vattulainen, Pere Roca-Cusachs, Franck Perez, Gaelle Boncompain, Stéphanie Miserey, Johanna Ivaska

Constitutive integrin endocytosis and recycling control cell movement and morphology. In contrast, the role of newly synthesized integrins delivered via the biosynthetic pathway has been largely overlooked. We used the retention using selective hooks system to monitor the localization of new…

Journal of Cell Biology, 2026, 225 (2), pp.e202508155. ⟨10.1083/jcb.202508155⟩. ⟨hal-05491533⟩

  • Article dans une revue

Randomized, multicenter Phase III trial of adjuvant chemotherapy with modified FOLFIRINOX versus capecitabine or gemcitabine in patients with resected ampullary adenocarcinoma

Gael S Roth, Jérôme Cros, Cindy Neuzillet, Emilie Barbier, Meriem Guarssifi, Amel Bennacer, Michel Ducreux, Marie Muller, Julien Edeline, Sylvain Manfredi, Nicolas Williet, Nelson Dusetti, Pierre Laurent-Puig, Victoire Ruffino, Brice Chanez, Rémy Nicolle, Julien Taieb, David Malka

Background: Ampullary adenocarcinoma (AAC) is a rare and aggressive cancer with a 5-year overall survival (OS) rate ranging from 30% to 67% after resection due to a high recurrence rate. Yet, adjuvant therapy's role is still debated. Recent French FFCD-AC cohort study highlighted that adjuvant…

Digestive and Liver Disease, 2026, 58, pp.308-314. ⟨10.1016/j.dld.2026.01.211⟩. ⟨hal-05509432⟩

Toutes les publications sur HAL

Contacts

Adresse postale

Biologie Cellulaire et Cancer, Institut Curie, 26 rue d’Ulm, 75248 Paris Cedex 05 France
Adresse physique
Biologie Cellulaire et Cancer
Institut Curie
26 rue d’Ulm
75248 Paris Cedex 05 France
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