Biologie Cellulaire et Cancer

• Article dans une revue

Chemically Responsive Protein Switches for the Precise Control of Biological Activities

Jaime Franco Pinto, Naama Drahy, Séverine Divoux, Franck Perez, Arnaud Gautier

ACS Chemical Biology, 2026, ⟨10.1021/acschembio.6c00360⟩. ⟨hal-05699932⟩

• Article dans une revue

IP47-03 A UNIVERSAL MOLECULAR MAP OF BLADDER CANCER: FROM CELL LINES IN VITRO TO TUMORS AND BACK USING CO-REGULATORY NETWORKS

Gautier Marcq, Konstantinos Geles, Geoffrey Palwak, Wajdi Dhifli, Pontus Eriksson, Carina Bernardo, Cagatay Guenes, Isabelle Bernard-Pierrot, Gottfrid Sjödahl, Yves Allory, Francois Radvanyi, Mohamed Elati

The Journal of Urology, 2026, 215 (5S), ⟨10.1097/01.JU.0001191556.17107.c7.03⟩. ⟨hal-05627761⟩

• Article dans une revue

A universal molecular map of bladder cancer: from cell lines in vitro to tumors and back using co-regulatory networks

G. Marcq, K. Geles, Wajdi Dhifli, P. Eriksson, C. Bernardo, C. Guenes, I. Bernard-Pierrot, G. Sjödahl, Y. Allory, F. Radvanyi, M. Elati

European Urology, 2026, 89, pp.S1-S2. ⟨10.1016/S0302-2838(26)00194-6⟩. ⟨hal-05591896⟩

• Article dans une revue

VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement

Somya Vats, Pedro Dionisio, Quentin Lemercier, Raphael Pineau, Ludivine Therreau, Joanna Lipecka, Béatrice Cholley, Jean-Baptiste Moog, Jose Wojnacki, Céline Keime, Diana Zala, Philippe Bun, Sofia Freire, Neuza Domingues, Lydia Danglot, Ida Chiara Guerrera, Cédric Delevoye, Eric Chevet, Nuno Raimundo, Thierry Galli

Late endosomal secretion is an unconventional secretion mechanism that depends on the SNARE protein VAMP7. We previously showed that VAMP7 mediates the secretion of the ER protein Reticulon3. However, the functional relevance and molecular mechanism of this secretory pathway remain unclear. Here,…

Nature Communications, 2026, ⟨10.1038/s41467-026-69900-4⟩. ⟨inserm-05532465⟩