• Biologie
  • Santé

Biologie Cellulaire et Cancer

  • Unité mixte de recherche

Publications sur HAL - Archive ouverte

Toutes les publications sur HAL
  • Article dans une revue

First-line chemotherapy with selective internal radiation therapy for intrahepatic cholangiocarcinoma

Nicolas Adamus, Julien Edeline, Julie Henriques, Nadim Fares, Thierry Lecomte, Anthony Turpin, Dewi Vernerey, Mathilde Vincens, Brice Chanez, David Tougeron, Christophe Tournigand, Eric Assenat, Matthieu Delaye, Sylvain Manfredi, Olivier Bouché, Nicolas Williet, Angélique Vienot, Lorraine Blaise, Léo Mas, Cindy Neuzillet, Alice Boilève, Gael S. Roth

Background and Aims: Selective internal radiation therapy (SIRT) is a promising option for liver-only unresectable intrahepatic cholangiocarcinoma (iCCA). The Real-SIRTCCA study retrospectively assessed the benefit of adding SIRT to chemotherapy in this setting within the French nationwide…

JHEP Reports Innovation in Hepatology, 2025, 7 (2), pp.101279. ⟨10.1016/j.jhepr.2024.101279⟩. ⟨hal-04932838⟩

  • Article dans une revue

DeepCristae, a CNN for the restoration of mitochondria cristae in live microscopy images

Salomé Papereux, Ludovic Leconte, Cesar Augusto Valades-Cruz, Tianyan Liu, Julien Dumont, Zhixing Chen, Jean Salamero, Charles Kervrann, Anaïs Badoual

Mitochondria play an essential role in the life cycle of eukaryotic cells. However, we still don't know how their ultrastructure, like the cristae of the inner membrane, dynamically evolves to regulate these fundamental functions, in response to external conditions or during interaction with…

Communications Biology, In press, pp.1-30. ⟨10.1101/2023.07.05.547594⟩. ⟨hal-04295317v1⟩

  • Article dans une revue

Basal/squamous and Mixed subtype bladder cancers present poor outcomes after neoadjuvant chemotherapy in the VESPER trial

C.S. Groeneveld, C. Pfister, S. Culine, V. Harter, C. Krucker, J. Fontugne, V. Dixon, N. Sirab, I. Bernard-Pierrot, A. de Reyniès, F. Radvanyi, Y. Allory, G. Pignot, J.P. Fendler, L. Guy, G. Verhoest, N. Mottet, A. Doerfler, S. Abadie-Lacourtoisie, A. Azzouzi, P. Mongiat, L. Geoffrois, P. Eschwege, F. Di Fiore, G. Roubaud, J.L. Hoepffner, P. Barthelemy, H. Lang, E. Voog, E. Mandron, J.M. Tourani, C. Serrrate, A. Colau, C. Saldana, A. de La Taille, T. Nguyen, F. Kleinclauss, Y. Loriot, J. Irani, J.C. Eymard, S. Larre, O. Huillard, M. Zerbib, F. Rolland, J. Rigaud, N. Houede, S. Droupy, G. Malouf, M. Roupret, S. Vieillot, N. Letang, T. Lharidon, N. Gaschignard, W. Hilgers, J.L. Davin

Background - Neoadjuvant chemotherapy (NAC) is the standard treatment for muscle-invasive bladder cancer (MIBC), yet 40% of patients progress, emphasizing the need for biomarkers predictive for response or chemoresistance. Gene expression-based subtypes may serve as biomarkers, though which…

Annals of Oncology, 2025, 36 (1), pp.89-98. ⟨10.1016/j.annonc.2024.09.008⟩. ⟨hal-04780573⟩

  • Article dans une revue

Forebrain Eml1 depletion reveals early centrosomal dysfunction causing subcortical heterotopia

Donia Zaidi, Kaviya Chinnappa, Berfu Nur Yigit, Valeria Viola, Carmen Cifuentes-Diaz, Ammar Jabali, Ana Uzquiano, Emilie Lemesre, Franck Perez, Julia Ladewig, Julien Ferent, Nurhan Ozlu, Fiona Francis

Mechanisms leading to abnormal distribution of neural progenitors during cortical development in the context of subcortical heterotopia associated with EML1 mutations remain unknown. Using a forebrain-specific mouse model and mutant human cells, this work innovatively demonstrates that by restoring…

Journal of Cell Biology, 2024, 223 (12), ⟨10.1083/jcb.202310157⟩. ⟨hal-04721394⟩

Contact details

Adresse postale

Biologie Cellulaire et Cancer, Institut Curie, 26 rue d’Ulm, 75248 Paris Cedex 05 France
Adresse physique
Biologie Cellulaire et Cancer
Institut Curie
26 rue d’Ulm
75248 Paris Cedex 05 France
1