Institut parisien de chimie moléculaire | IPCM

• Article dans une revue

Deferasirox derivatives as inhibitors of Kallikrein‐related peptidases associated to neurodegenerative diseases

Rilès Boumali, Elodie David, Nancy Chaaya, Morane Lucas, Sabrina Aït Amiri, Valérie Lefort, Anthony Nina Diogo, Michèle Salmain, Isabelle Petropoulos, Vincent Corcé, Chahrazade El Amri, Candice Botuha

Kallikrein‐related peptidases are a family of serine proteases which loss of activity regulation has been particularly linked to neurodegenerative diseases. Moreover, iron overload is also a key process in some of these leading pathological conditions, particularly Alzheimer’s disease. We…

ChemMedChem, 2025, pp.e202500187. ⟨10.1002/cmdc.202500187⟩. ⟨hal-05025558⟩

• Article dans une revue

Bioorthogonal Post‐Labeling Reveals Nuclear Localization of a Highly Cytotoxic Half‐sandwich Ir(III) Tetrazine Complex in Live Cells

Alfonso Annunziata, Sadek Amhaz, Jérémy Forté, Geoffrey Gontard, Romain Morichon, Joëlle Sobczak-Thépot, Michele Salmain

Intracellular imaging of anticancer metallodrugs often relies on pre‐labeling with organic fluorophores, which significantly affects their physicochemical properties and intracellular distribution. On the other hand, the reported post‐labeling strategies based on click‐chemistry reactions require…

ChemBioChem, 2025, pp.e202500090. ⟨10.1002/cbic.202500090⟩. ⟨hal-05020776⟩

• Article dans une revue

Structural insights into nanofibers formed by templated polymerization-induced self-assembly through combined SANS and AFM characterizations

Gaëlle Mellot, Mathieu Chevereau, Laurent Bouteiller, François Stoffelbach, Marylene Vayer, Jutta Rieger, Christophe Sinturel

Journal of Molecular Liquids, 2025, 424, pp.127104. ⟨10.1016/j.molliq.2025.127104⟩. ⟨hal-05033481⟩

• Article dans une revue

Design of photomagnetic ultra-thin films by electrodeposition of switchable cyanide-bridged Fe 4 Co 4 complexes, Conception de films photomagnétiques ultra-minces par électrodéposition de complexes Fe 4 Co 4 pontés au cyanure commutables

Amina Benchohra, Jessem Landoulsi, Niéli Daffé, Christophe Méthivier, Emmanuel Maisonhaute, Laure Fillaud, Jan Dreiser, Michal Studniarek, Marie‐anne Arrio, Yanling Li, Sofia Frida Russi, David Kreher, Rodrigue Lescouëzec

Preparing thin-films of molecular polymetallic materials remains one of the current limitations in the implementation of polymetallic complexes into devices. The hurdle was tackled here using an electrochemical route for depositing the cyanido-bridged polymetallic complex {Tl[Fe II (2-TPhTp)(CN) 3…, La préparation de couches minces de matériaux polymétalliques moléculaires reste l'une des limitations actuelles dans la mise en œuvre de complexes polymétalliques dans des dispositifs. Cet obstacle a été abordé ici en utilisant une voie électrochimique pour déposer le complexe polymétallique…

Small, 2025, ⟨10.1002/smll.202408917⟩. ⟨hal-05011706⟩