Laboratoire de biologie intégrative des modèles marins | LBI2M

• Article dans une revue

A duo of fungi and complex and dynamic bacterial community networks contribute to shape the Ascophyllum nodosum holobiont

Coralie Rousseau, Gwenn Tanguy, Erwan Legeay, Samuel Blanquart, Arnaud Belcour, Sylvie Rousvoal, Philippe Potin, Catherine Leblanc, Simon Dittami

Background The brown alga Ascophyllum nodosum and its microbiota form a dynamic functional entity named holobiont. Some microbial partners may play a role in seaweed health through bioactive compounds crucial for normal morphology, development, and physiological acclimation. However, the full…

Environmental Microbiome, 2025, pp.1-53. ⟨10.1186/s40793-025-00825-z⟩. ⟨hal-05413201⟩

• Article dans une revue

Professor Dieter G. Müller's legacy in algal developmental biology and phycology (1935–2025)

Wilhelm Boland, Ingo Maier, Akira Peters, Hiroshi Kawai, Renato Westermeier, J. Mark Cock, Susana Coelho, Claire Gachon

Journal of Phycology, 2025, 61 (6), pp.1534-1535. ⟨10.1111/jpy.70106⟩. ⟨hal-05471589⟩

• Article dans une revue

Life-cycle-related gene expression patterns in the brown algae

Pélagie Ratchinski, Olivier Godfroy, Benjamin Noel, Jean-Marc Aury, J. Mark Cock

Brown algae are important primary constituents of marine coastal ecosystems, characterised by complex life cycles and various levels of complex multicellular development. However, the molecular processes that underlie development and life cycle progression in the brown algae remain poorly…

eLife, 2025, 14, ⟨10.7554/elife.107449⟩. ⟨hal-05374384⟩

• Article dans une revue

Synthesis of 1H-Pyrrolo[3,2-g]isoquinoline Derivatives as Ligands Targeting Haspin Kinase

Killian Malosse, Béatrice Josselin, Sandrine Ruchaud, Fabrice Anizon, Francis Giraud, Pascale Moreau

A new series of 1H-pyrrolo[3,2-g]isoquinolines, diversely substituted at the 3-position either by a heteroaromatic scaffold or by propionate/acrylate side chains, were synthesized and evaluated as Haspin kinase inhibitors. The results of the kinase inhibitory potency study demonstrated that some of…

Molecules, 2025, 30 (22), pp.4388. ⟨10.3390/molecules30224388⟩. ⟨hal-05447996⟩